Publications
Real-time evaluation of glioblastoma growth in patient-specific zebrafish xenografts
Almstedt E, Rosén E, Gloger M, Stockgard R, Hekmati N, Koltowska K, Krona C, Nelander S.
Neuro Oncol. 2022 May 4;24(5):726-738.
Comparative epigenetic analysis of tumour initiating cells and syngeneic EPSC-derived neural stem cells in glioblastoma
Vinel C, Rosser G, Guglielmi L, Constantinou M, Pomella N, Zhang X, Boot JR, Jones TA, Millner TO, Dumas AA, Rakyan V, Rees J, Thompson JL, Vuononvirta J, Nadkarni S, El Assan T, Aley N, Lin YY, Liu P, Nelander S, Sheer D, Merry CLR, Marelli-Berg F, Brandner S, Marino S.
Nat Commun. 2021 Oct 21;12(1):6130.
Autocrine signaling can explain the emergence of Allee effects in cancer cell populations
Gerlee P, Altrock PM, Malik A, Krona C, Nelander S.
PLoS Comput Biol. 2022 Mar 3;18(3):e1009844.
Modeling glioblastoma heterogeneity as a dynamic network of cell states
Larsson I, Dalmo E, Elgendy R, Niklasson M, Doroszko M, Segerman A, Jörnsten R, Westermark B, Nelander S.
Mol Syst Biol. 2021 Sep;17(9):e10105.
NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1
Marques C, Unterkircher T, Kroon P, Oldrini B, Izzo A, Dramaretska Y, Ferrarese R, Kling E, Schnell O, Nelander S, Wagner EF, Bakiri L, Gargiulo G, Carro MS, Squatrito M.
Elife. 2021 Aug 17;10:e64846.
Inferring the experimental design for accurate gene regulatory network inference
Seçilmiş D, Hillerton T, Nelander S, Sonnhammer ELL.
Bioinformatics. 2021 May 12:btab367.
Monotherapy efficacy of blood-brain barrier permeable small molecule reactivators of protein phosphatase 2A in glioblastoma
Merisaari J, Denisova OV, Doroszko M, Le Joncour V, Johansson P, Leenders WPJ, Kastrinsky DB, Zaware N, Narla G, Laakkonen P, Nelander S, Ohlmeyer M, Westermarck J.
Brain Commun. 2020 Jan 11;2(1):fcaa002.
A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma
Johansson P, Krona C, Kundu S, Doroszko M, Baskaran S, Schmidt L, Vinel C, Almstedt E, Elgendy R, Elfineh L, Gallant C, Lundsten S, Ferrer Gago FJ, Hakkarainen A, Sipilä P, Häggblad M, Martens U, Lundgren B, Frigault MM, Lane DP, Swartling FJ, Uhrbom L, Nestor M, Marino S, Nelander S.
Cell Rep. 2020 Jul 14;32(2):107897.
HCN Channel Activity Balances Quiescence and Proliferation in Neural Stem Cells and Is a Selective Target for Neuroprotection During Cancer Treatment
Johard H, Omelyanenko A, Fei G, Zilberter M, Dave Z, Abu-Youssef R, Schmidt L, Harisankar A, Vincent CT, Walfridsson J, Nelander S, Harkany T, Blomgren K, Andäng M.
Mol Cancer Res. 2020 Oct;18(10):1522-1533.
Growth-Inhibitory Activity of Bone Morphogenetic Protein 4 in Human Glioblastoma Cell Lines Is Heterogeneous and Dependent on Reduced SOX2 Expression
Dalmo E, Johansson P, Niklasson M, Gustavsson I, Nelander S, Westermark B.
Mol Cancer Res. 2020 Jul;18(7):981-991. doi: 10.1158/1541-7786.MCR-19-0638.
PMID: 31900415; PMCID: PMC6941971.
Real-time evaluation of glioblastoma growth in patient-specific zebrafish xenografts
Almstedt E, Rosén E, Gloger M, Stockgard R, Hekmati N, Koltowska K, Krona C, Nelander S.
Neuro Oncol. 2022 May 4;24(5):726-738.
PMID: 35490730; PMCID: PMC9009924.
Comparative epigenetic analysis of tumour initiating cells and syngeneic EPSC-derived neural stem cells in glioblastoma
Vinel C, Rosser G, Guglielmi L, Constantinou M, Pomella N, Zhang X, Boot JR, Jones TA, Millner TO, Dumas AA, Rakyan V, Rees J, Thompson JL, Vuononvirta J, Nadkarni S, El Assan T, Aley N, Lin YY, Liu P, Nelander S, Sheer D, Merry CLR, Marelli-Berg F, Brandner S, Marino S.
Nat Commun. 2021 Oct 21;12(1):6130.
PMID: 34615747; PMCID: PMC8533345.
Autocrine signaling can explain the emergence of Allee effects in cancer cell populations
Gerlee P, Altrock PM, Malik A, Krona C, Nelander S.
PLoS Comput Biol. 2022 Mar 3;18(3):e1009844.
PMID: 35275681; PMCID: PMC8915275.
Modeling glioblastoma heterogeneity as a dynamic network of cell states
Larsson I, Dalmo E, Elgendy R, Niklasson M, Doroszko M, Segerman A, Jörnsten R, Westermark B, Nelander S.
Mol Syst Biol. 2021 Sep;17(9):e10105.
PMID: 34530610; PMCID: PMC8430723.
NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1
Marques C, Unterkircher T, Kroon P, Oldrini B, Izzo A, Dramaretska Y, Ferrarese R, Kling E, Schnell O, Nelander S, Wagner EF, Bakiri L, Gargiulo G, Carro MS, Squatrito M.
Elife. 2021 Aug 17;10:e64846.
PMID: 34421016; PMCID: PMC8352079.
Inferring the experimental design for accurate gene regulatory network inference
Seçilmiş D, Hillerton T, Nelander S, Sonnhammer ELL.
Bioinformatics. 2021 May 12:btab367.
PMID: 33858493; PMCID: PMC8251454.
Monotherapy efficacy of blood-brain barrier permeable small molecule reactivators of protein phosphatase 2A in glioblastoma
Merisaari J, Denisova OV, Doroszko M, Le Joncour V, Johansson P, Leenders WPJ, Kastrinsky DB, Zaware N, Narla G, Laakkonen P, Nelander S, Ohlmeyer M, Westermarck J.
Brain Commun. 2020 Jan 11;2(1):fcaa002.
PMID: 32007595; PMCID: PMC6983439.
A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma
Johansson P, Krona C, Kundu S, Doroszko M, Baskaran S, Schmidt L, Vinel C, Almstedt E, Elgendy R, Elfineh L, Gallant C, Lundsten S, Ferrer Gago FJ, Hakkarainen A, Sipilä P, Häggblad M, Martens U, Lundgren B, Frigault MM, Lane DP, Swartling FJ, Uhrbom L, Nestor M, Marino S, Nelander S.
Cell Rep. 2020 Jul 14;32(2):107897.
PMID: 32608799; PMCID: PMC7388369.
HCN Channel Activity Balances Quiescence and Proliferation in Neural Stem Cells and Is a Selective Target for Neuroprotection During Cancer Treatment
Johard H, Omelyanenko A, Fei G, Zilberter M, Dave Z, Abu-Youssef R, Schmidt L, Harisankar A, Vincent CT, Walfridsson J, Nelander S, Harkany T, Blomgren K, Andäng M.
Mol Cancer Res. 2020 Oct;18(10):1522-1533.
PMID: 32758616; PMCID: PMC7522241.
Growth-Inhibitory Activity of Bone Morphogenetic Protein 4 in Human Glioblastoma Cell Lines Is Heterogeneous and Dependent on Reduced SOX2 Expression
Dalmo E, Johansson P, Niklasson M, Gustavsson I, Nelander S, Westermark B.
Mol Cancer Res. 2020 Jul;18(7):981-991.
PMID: 32004222; PMCID: PMC7522682.